This table summarizes the total number of protease genes in the human,
mouse and rat genomes, including orthologous genes, and human-,
mouse- or rat-specific genes. Some functional genes have been
inactivated by deleterious mutations in one species, and they are
mentioned, although they are not included in the final count.
| Catalytic
class |
||||||
|---|---|---|---|---|---|---|
| Total | Aspartic | Cysteine | Metallo | Serine | Threonine | |
| Human proteases | 570 | 21 | 153 | 191 | 178 | 27 |
| Mouse proteases | 656 | 27 | 170 | 206 | 227 | 26 |
| Rat
proteases |
646 |
24 |
167 |
200 |
226 |
29 |
| Rat/human orthologs | 540 | 21 | 142 | 185 | 166 | 26 |
| Rat/mouse orthologs | 602 |
24 |
158 |
199 |
195 |
26 |
| Rat-specific | 43 |
0 | 9 |
1 |
30 | 3 |
| Rodent-specific | 62 |
3 |
15 |
14 | 30 |
0 |
| Human gene/rat pseudogene | 6 |
0 |
1 |
2 |
3 |
0 |
| Rat gene/human pseudogene | 24 |
1 |
1 |
8 |
14 |
0 |
| Mouse
gene/rat pseudogene |
10 |
1 |
1 |
4 |
4 |
0 |
| Rat
gene/mouse pseudogene |
2 |
0 |
1 |
0 |
1 |
0 |