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Class
Family
Aspartyl proteases
___
A01
A02
A22
Ax1
Cysteine proteases
___
C01
C02
C12
C13
C14
C15
C19
C26
C44
C46
C48
C50
C54
C56
C64
C65
C67
C69
C78
C80
C85
C86
Cx1
Metalloproteases
___
M01
M02
M03
M08
M10
M12
M13
M14
M16
M17
M18
M19
M20
M22
M24
M28
M38
M41
M43
M48
M49
M50
M54
M67
M76
Mx1
Mx2
Serine proteases
___
S01
S08
S09
S10
S12
S14
S16
S26
S28
S33
S53
S54
S59
S60
S68
Sx1
Sx2
Sx3
Threonine proteases
___
T01
T02
T03
Search
Terms
Sequence
Additional information
Protease inhibitors
Degradome landscape
Numbers
Domains
Human/mouse differences
Diseases
Selected structures
Software
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Family
Name
Human
Chimpanzee
Mouse
Rat
S01
kallikrein hK1
KLK1
KLK1
Klk1
kallikrein hK2
KLK2
KLK2
#mGk25
#Klk2
kallikrein hK3
KLK3
KLK3
#Klk3
kallikrein hK4
KLK4
KLK4
mKlk4
Klk4
kallikrein hK5
KLK5
KLK5
mKlk5
Klk5
kallikrein hK6
KLK6
KLK6
mKlk6
Klk6
kallikrein hK7
KLK7
KLK7
mKlk7
Klk7
kallikrein hK8
KLK8
KLK8
mKlk8
Klk8
kallikrein hK9
KLK9
KLK9
mKlk9
Klk9
kallikrein hK10
KLK10
KLK10
mKlk10
Klk10
kallikrein hK11
KLK11
KLK11
mKlk11
Klk11
kallikrein hK12
KLK12
KLK12
mKlk12
Klk12
kallikrein hK13
KLK13
KLK13
mKlk13
Klk13
kallikrein hK14
KLK14
KLK14
mKlk14
Klk14
kallikrein hK15
KLK15
KLK15
mKlk15
Klk15
glandular kallikrein mK1
mGk1
glandular kallikrein mK3
mGk3
glandular kallikrein mK4
mGk4
glandular kallikrein mK5
mGk5
glandular kallikrein mK6
mGk6
glandular kallikrein mK8
mGk8
glandular kallikrein mK9
mGk9
glandular kallikrein mK11
mGk11
glandular kallikrein mK16
mGk16
glandular kallikrein mK21
mGk21
glandular kallikrein mK22
mGk22
glandular kallikrein mK24
mGk24
glandular kallikrein mK26
mGk26
glandular kallikrein mK27
mGk27
rat kallikrein
K-32
glandular kallikrein rK1/NGFg
rGk1
glandular kallikrein 2/tonin
rGk2
glandular kallikrein 3
rGk3
glandular kallikrein 7
rGk7
glandular kallikrein 8
rGk8
glandular kallikrein 9
rGk9
glandular kallikrein rKlk10
rGk10
glandular kallikrein rKlk11
rGk11
glandular kallikrein rKlk12
rGk12
thrombin
F2
F2
F2
F2
coagulation factor VIIa
F7
F7
F7
F7
coagulation factor IXa
F9
F9
F9
F9
coagulation factor Xa
F10
F10
F10
F10
coagulation factor XIa
F11
F11
F11
F11
coagulation factor XIIa
F12
F12
F12
F12
protein C
PROC
PROC
Proc
Proc
protein Z
PROZ
PROZ
Proz
Proz
plasma kallikrein
KLKB1
KLKB1
Klkb1
Klkb1
HGF activator
HGFAC
HGFAC
Hgfac
Hgfac
hyaluronan-binding ser-protease
HABP2
HABP2
Habp2
Habp2
protein C-like
PROCL
PROCL
Procl
Procl
mastin
#MASTIN
#MASTIN
Prss34/Mastin
Prss34/Mastin
tryptase alpha/beta 1
TPS/TPSB1
TPS/TPSB1
Tpsab1
Tpsab1
tryptase beta 2
TPSAB1
TPSAB1
Tpsb2
Tpsb2
tryptase gamma 1
TPSG1
TPSG1
Tpsg1
Tpsg1
marapsin
PRSS27
PRSS27
Prss27/Mpn
Prss27
tryptase homolog 2/EOS
PRSS33
PRSS33
Prss33/Eos
Prss33
tryptase homolog 3
#TESSP1
#TESSP1
Tessp1
Tessp1
testisin
PRSS21
PRSS21
Prss21
Prss21
brain serine proteinase 2
PRSS22
PRSS22
Prss22
Prss22
implantation serine protease 1
Prss28/Isp1
#Prss28/Isp1
implantation serine protease 2
#ISP2
#ISP2
Prss29/Isp2
Prss29/Isp2
implantation serine protease 2-like
Isp2l
intestinal serine protease 1
#DISP
#DISP
Tmprss8/Disp
Tmprss8/Disp
intestinal serine protease 2
Prss32/Disp2
Prss32/Disp2
tryptase delta 1
TPSD1
TPSD1
prostasin
PRSS8
PRSS8
Prss8
Prss8
epidermis-specific SP-like
ESSPL
ESSPL
Esspl
Esspl
marapsin 2
MPN2
MPN2
Mpn2
Mpn2
testis-specific protein tsp50
TSP50
TSP50
Tsp50
#Tsp50
testis serine protease 2
TESSP2
TESSP2
Tessp2
Tessp2
testis serine protease 3
#TESSP3
#TESSP3
Tessp3
Tessp3
testis serine protease 4
#TESSP4
#TESSP4
Tessp4
#Tessp4
testis serine protease 5
TESSP5
TESSP5
Tessp5
Tessp5
testis serine protease 6
#TESSP6
#TESSP6
Tessp6
Tessp6
TESP1
Tesp1
Tesp1
TESP2
#TESP2
#TESP2
Tesp2
Tesp2
TESP3
#TESP3
#TESP3
Tesp3
Tesp3
granzyme B
GZMB
GZMB
Gzmb
Gzmb
granzyme H
GZMH
GZMH
Gzmc
Gzmc
cathepsin G
CTSG
CTSG
Ctsg
Ctsg
chymase
CMA1
CMA1
Cma1
Cma1
mast cell protease 1
Mcpt1
Mcpt1
mast cell protease 4
Mcpt4
Mcpt4
mast cell protease 8
Mcpt8
Mcpt8
granzyme G
Gzmg
Gzmg
granzyme N
Gzmn
Gzmn
granzyme O
Gzmo
Gzmo
granzyme D
Gzmd
granzyme E
Gzme
granzyme F
Gzmf
mast cell protease 2
Mcpt2
mast cell protease 9
Mcpt9
mast cell protease 10
Cma2
mast cell protease L
Mcptl
rat mast cell protease 2
Mcpt2
rat mast cell protease 1-like 1
Mcpt1l1
rat mast cell protease 1-like 2
Mcpt1l2
rat mast cell protease 1-like 3
Mcpt1l3
rat mast cell protease 1-like 4
Mcpt1l4
rat mast cell protease 3
Mcpt3
rat mast cell protease 4
rMcpt4
rat mast cell protease 4-like 1
Mcpt4l1
rat mast cell protease 8-like 1
Mcpt8l1
rat mast cell protease 8-like 2
Mcpt8l2
rat mast cell protease 8-like 3
Mcpt8l3
rat mast cell protease 9
Mcpt9
granzyme B-like 1
Gzmbl1
gramzyme l3
Gzmbl2
natural killer cell protease 7
Rnkp7l
granzyme C-like 1
Gzmcl1
granzyme C-like 2
Gzmcl2
granzyme C-like 3
Gzmcl3
granzyme A
GZMA
GZMA
Gzma
Gzma
granzyme K
GZMK
GZMK
Gzmk
Gzmk
granzyme M
GZMM
GZMM
Gzmm
Gzmm
proteinase 3
PRTN3
PRTN3
Prtn3
Prtn3
neutrophil elastase
ELA2
ELA2
Ela2
Ela2
azurocidin
AZU1
AZU1
enteropeptidase
PRSS7
PRSS7
Prss7
Prss7
enteropeptidase-like
PRSS7L
PRSS7L
Prss7l
Prss7l
hepsin
HPN
HPN
Hpn
Hpn
HAT-like 2
#HATL2
#HATL2
Desc4/Hatl2
Desc4/Hatl2
HAT-like 3
#HATL3
#HATL3
Tmprss11c/Hatl3
Tmprss11c/Hatl3
corin
CORIN
CORIN
Corin
Corin
matriptase
ST14
ST14
St14/Mtsp1
St14/Mtsp1
epitheliasin
TMPRSS2
TMPRSS2
Tmprss2
Tmprss2
transmembrane Ser-protease 3
TMPRSS3
TMPRSS3
Tmprss3
Tmprss3
transmembrane Ser-protease 4
TMPRSS4
TMPRSS4
Tmprss4
Tmprss4
spinesin
TMPRSS5
TMPRSS5
Tmprss5
Tmprss5
matriptase-2
TMPRSS6
TMPRSS6
Tmprss6
Tmprss6
matriptase-3
TMPRSS7
TMPRSS7
Tmprss7
Tmprss7
polyserase-I
TMPRSS9
TMPRSS9
Tmprss9
Tmprss9
TMPRSS11A
TMPRSS11A
TMPRSS11A
Tmprss11a
HAT-like 5
TMPRSS11B
TMPRSS11B
Tmprss11b
Tmprss11b
airway-trypsin-like protease
TMPRSS11D
TMPRSS11D
Tmprss11d
Tmprss11d
DESC1 protease
TMPRSS11E
TMPRSS11E
Tmprss11e
Tmprss11e
HAT-like 4
TMPRSS11F
TMPRSS11F
Tmprss11f
Tmprss11f
HAT-related protease
TMPRSS12
TMPRSS12
Tmprss12
Tmprss12
membrane-type mosaic Ser-prot.
TMPRSS13
TMPRSS13
Tmprss13
Tmprss13
polyserase-2
PRSS36
PRSS36
Prss36
Prss36
polyserase-3
POL3S
POL3S
Pol3s
Pol3s
oviductin-like/ovochymase-2
OVCH2
OVCH2
Ovch2
Ovch2
ovochymase-like
OVCH1
OVCH1
chymotrypsin B
CTRB1
CTRB1
Ctrb1
Ctrb1
chymopasin
CTRL
CTRL
Ctrl
Ctrl
chymotrypsin C
CTRC
CTRC
Ctrc
Ctrc
cationic trypsin
PRSS1
PRSS1
Prss1
Prss1
trypsin 10
#TRY10
#TRY10
Try10
Try10
anionic trypsin (II)
PRSS2
PRSS2
Prss2
Prss2
trypsin C
#TRY6
#TRY6
Try10l
#Try10l
trypsin 15
#TRY15
#TRY15
Try15
Try15
trypsin X2
TRYX2
TRYX2
Tryx2
Tryx2
mesotrypsin
PRSS3
PRSS3
Prss3
Prss3
trypsin 1
Try1
Try1
trypsin 9
Tesp4/Try9
Try9
trypsin 12
Try12
Try12
trypsin 5
Try5
TryV-A
trypsin X3
Tryx3
Tryx3
trypsin X4
Tryx4
Tryx4
trypsin 4
Try4
Try4
trypsin V
Try4l
trypsin X5
Tryx5
Tryx5
pancreatic elastase
#ELA1
#ELA1
Ela1
Ela1
pancreatic elastase II (IIA)
ELA2A
ELA2A
Ela2a
Ela2a
pancreatic endopeptidase E (A)
ELA3A
ELA3A
Ela3a
pancreatic endopeptidase E (B)
ELA3B
ELA3B
Ela3b
Ela3b
pancreatic elastase II form B
ELA2B
ELA2B
complement component 2
C2
C2
C2
C2
complement factor B
CFB
CFB
Cfb
Cfb
complement C1r-homolog
C1RL
C1RL
C1rl
C1rl
complement component C1ra
C1R
C1R
C1r
C1r
complement component C1rb
C1rb
complement component C1sa
C1S
C1S
C1sa
C1s
complement component C1sb
C1sb
complement factor D
DF
DF
Cfd
Cfd
complement factor D-like
PRSSL1
PRSSL1
Prssl1
Prssl1
complement factor I
CFI
CFI
Cfi
Cfi
MASP1/3
MASP1/3
MASP1/3
Masp1/3
Masp1/3
MASP2
MASP2
MASP2
Masp2
Masp2
neurotrypsin
PRSS12
PRSS12
Prss12
Prss12
u-plasminogen activator
PLAU
PLAU
Plau
Plau
t-plasminogen activator
PLAT
PLAT
Plat
Plat
plasminogen
PLG
PLG
Plg
Plg
hepatocyte growth factor
HGF
HGF
Hgf
Hgf
macrophage-stimulating protein
MST1
MST1
Mst1
Mst1
apolipoprotein (a)
LPA
LPA
acrosin
ACR
ACR
Acr
Acr
haptoglobin-1
HP
HP
Hp
Hp
haptoglobin-related protein
HPR
HPR
haptoglobin primate
HPP
osteoblast serine protease
HTRA1
HTRA1
Htra1
Htra1
HTRA2
HTRA2
HTRA2
Htra2
Htra2
HTRA3
HTRA3
HTRA3
Htra3
Htra3
HTRA4
HTRA4
HTRA4
Htra4
Htra4
umbelical vein proteinase
PRSS23
PRSS23
Prss23
Prss23
similar to SPUVE
PRSS35
PRSS35
Prss35
Prss35
plasma-kallikrein-like 1
KLKBL1
KLKBL1
Klkbl1
Klkbl1
plasma-kallikrein-like 2
KLKBL2
KLKBL2
Klkbl2
plasma-kallikrein-like 3
#KLKBL3
#KLKBL3
Klkbl3
plasma-kallikrein-like 4
KLKBL4
KLKBL4
Klkbl4
Klkb4
similar to Arabidopsis Ser-prot.
TYSND1
TYSND1
Tysnd1
Tysnd1
Ppnx
#PPNX
#PPNX
Ppnx
Ppnx
S08
site-1 protease
MBTPS1
MBTPS1
Mbtps1
Mbtps1
proprotein convertase 9
PCSK9
PCSK9
Pcsk9
Pcsk9
tripeptidyl-peptidase II
TPP2
TPP2
Tpp2
Tpp2
proprotein convertase 1
PCSK1
PCSK1
Pcsk1
Pcsk1
proprotein convertase 2
PCSK2
PCSK2
Pcsk2
Pcsk2
furin
PCSK3
PCSK3
Furin
Furin
proprotein convertase 4
PCSK4
PCSK4
Pcsk4
Pcsk4
proprotein convertase 5
PCSK5
PCSK5
Pcsk5
Pcsk5
PACE4 proprotein convertase
PCSK6
PCSK6
Pcsk6
Pcsk6
proprotein convertase 7
PCSK7
PCSK7
Pcsk7
Pcsk7
S09
prolyl oligopeptidase
PREP
PREP
Prep
Prep
prolyl oligopeptidase-like
PREPL
PREPL
Prepl
Prepl
dipeptidyl-peptidase 4
DPP4
DPP4
Dpp4
Dpp4
dipeptidyl-peptidase 6
DPP6
DPP6
Dpp6
Dpp6
dipeptidyl-peptidase 8
DPP8
DPP8
Dpp8
Dpp8
dipeptidyl-peptidase 9
DPP9
DPP9
Dpp9
Dpp9
dipeptidyl-peptidase 10
DPP10
DPP10
Dpp10
Dpp10
seprase
FAP
FAP
Fap
Fap
acylaminoacyl-peptidase
APEH
APEH
Apeh
Apeh
family with sequence similarity 108, member B1
FAM108B1
FAM108B1
Fam108b1
Fam108b1
family with sequence similarity 108, member A1
FAM108A1
FAM108A1
Fam108a1
Fam108a1
family with sequence similarity 108, member C1
FAM108C1
FAM108C1
Fam108c1
Fam108c1
abhydrolase domain containing 13
ABHD13
ABHD13
Abhd13
Abhd13
abhydrolase domain containing 12
ABHD12
ABHD12
Abhd12
Abhd12
abhydrolase domain containing 12B
ABHD12B
ABHD12B
Abhd12b
Abhd12b
S10
lysosomal carboxypeptidase A
CTSA
CTSA
Ctsa
Ctsa
vitellogenic carboxypeptidase-L
CPVL
CPVL
Cpvl
Cpvl
serine carboxypeptidase 1
SCPEP1
SCPEP1
Scpep1
Scpep1
S12
beta lactamase
LACTB
LACTB
Lactb
Lactb
S14
endopeptidase Clp
CLPP
CLPP
Clpp
Clpp
S16
PIM1 endopeptidase
LONP1
LONP1
Lonp1
Lonp1
PIM2 endopeptidase
LONP2
LONP2
Lonp2
Lonp2
S26
signalase 18 kDa component
SEC11A
SEC11A
Sec11a
Sec11a
signalase 21 kDa component
SEC11C
SEC11C
Sec11c
Sec11c
signalase-like 1
FREM1
FREM1
Frem1
Frem1
mitoc. inner membrane protease 2
IMMP2L
IMMP2L
Immp2l
Immp2l
mitochondrial signal peptidase
IMMP1L
IMMP1L
Immp1l
Immp1
S28
lysosomal Pro-X C-peptidase
PRCP
PRCP
Prcp
Prcp
dipeptidyl-peptidase II
DPP7
DPP7
Dpp7
Dpp7
thymus-specific serine peptidase
PRSS16
PRSS16
Prss16
Prss16
S33
abhydrolase dom. containing 4
ABHD4
ABHD4
Abhd4
Abdh4
epoxide hydrolase
EPHX1
EPHX1
Ephx1
Ephx1
mesoderm-specific transcript
MEST
MEST
Mest
Mest
epoxyde hydrolase related protein
ABHD7
ABHD7
Abhd7
Abhd7
CGI-58
ABHD5
ABHD5
Abhd5
Abhd5
S41
retinol binding protein 3
RBP3
RBP3
Rbp3
Rbp3
S53
tripeptidyl-peptidase I
TPP1
TPP1
Tpp1
Tpp1
S54
rhomboid-like protein 1
RHBDL1
RHBDL1
Rhbdl1
Rhbdl1
rhomboid, veinlet-like 2
RHBDL2
RHBDL2
Rhbdl2
Rhbdl2
rhomboid, veinlet-like 3
RHBDL3
RHBDL3
Rhbdl3
Rhbdl3
rhomboid domain containing 1
RHBDD1
RHBDD1
Rhbdd1
Rhbdd1
rhomboid 5 homolog 2
RHBDF2
RHBDF2
Rhbdf2
Rhbdf2
rhomboid domain containing 2
RHBDD2
RHBDD2
Rhbdd2
Rhbdd2
presenilins-assoc. rhomboid like
PARL
PARL
Parl
Parl
rhomboid 5 homolog 1
RHBDF1
RHBDF1
Rhbdf1
Rhbdf1
S59
nucleoporin 98
NUP98
NUP98
Nup98
Nup98
S60
lactotransferrin
LTF
LTF
Ltf
Ltf
S68
PIDD auto-processing protein unit 1
PIDD
PIDD
Pidd
Pidd
Sx1
reelin
RELN
RELN
Reln
Reln
Sx2
heat shock protein 90kDa beta (Grp94), member 1/tumor rejection antigen (gp96)
HSP90B1
HSP90B1
Hsp90b1
Hsp90b1
heat shock 90kDa protein 1, alpha
HSP90AA1
HSP90AA1
Hsp90aa1
Hsp90aa1
heat shock 90kDa protein 1, beta
HSP90AB1
HSP90AB1
Hsp90ab1
Hsp90ab1
heat shock protein 75
TRAP1
TRAP1
Trap1
Trap1
Sx3
transthyretin
TTR
TTR
Ttr
Ttr
For problems or suggestions, please write to
Victor Quesada